In November 2025, The INTREPID Alliance announced the launch of the Antiviral Toolbox, an open-access resource to support the global research community in its efforts toward filling the gaps in antiviral R&D that is critical to global health security and the protection of communities worldwide. This curated platform provides easy access to a focused collection of tools and publications, including a Registry of Antiviral Compound Libraries, to help catalyze the identification and development of small-molecule antivirals.
The key components within the INTREPID Alliance Antiviral Toolbox include:
- Registry of Antiviral Compound Libraries: A curated list of accessible compound libraries for antiviral screening sourced from publicly disclosed academic institutions, corporate, and commercial vendor listings. An FAQ document is included on the site.
- Antiviral Development Landscape: INTREPID’s bi-annual landscape report and interactive pipeline, along with deep-dive topic reports, that provide a comprehensive analysis of small-molecule antiviral compounds in preclinical and clinical development globally.
- Drug Development Tools: Essential resources, including the published INTREPID Alliance Target Compound Profiles,4 Target Product Profiles,5 and cell and animal models for specific viral families, available to help drug discoverers and developers at all stages of research.
- Pro Bono Advisory Services: Opportunity for drug discoverers and developers to connect with INTREPID’s team of experts to discuss potential strategies and approaches to address challenges along their drug development journey.
The INTREPID Alliance has offered to provide a webinar on the Toolbox upon request.